City Rexall Drugs - Home of low prescription prices and friendly personal service
About Us

City Rexall Drugs started business as City Drug Store sometime between 1903 and 1906 in the small logging town of Picayune, Mississippi. In 1947 the business was purchased from the Stovall family by Ben and Johnnie Griffin. City Drug Store became a Rexall franchise in the 1950's. It was moved from it's original location on the corner of Canal Street and Main Street to the Alexander Shopping Center, Picayune's first shopping center in 1965 for better parking. In 1985 with the death of Ben Griffin, John Griffin, his youngest son, returned home to the family business and ran it with Johnnie until her retirement in 2002. Today City Rexall is still a family business with Ben Griffin's granddaughter, Sarah Barrack store manager.

Location:                                               Hours:                             
349 South Main Street                             Mon thru Fri 9AM to 6PM
Picayune, MS 39466                                 Saturday      9AM to 1:30PM
                                                              Sunday         Closed 

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